Antibodies that detect Dectin 2 can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA, Flow Cytometry and Immunocytochemistry. These antibodies target Dectin 2 in Human, Mouse, Rat and Non-human primate samples. Our Dectin 2...Antibodies that detect Dectin 2 can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA, Flow Cytometry and Immunocytochemistry. These antibodies target Dectin 2 in Human, Mouse, Rat and Non-human primate samples. Our Dectin 2 polyclonal, recombinant monoclonal and monoclonal antibodies are...Antibodies that detect Dectin 2 can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA, Flow Cytometry and Immunocytochemistry. These antibodies target Dectin 2 in Human, Mouse, Rat and Non-human primate samples. Our Dectin 2 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Sheep, Goat and Mouse. Find the Dectin 2 antibody that fits your needs. Choose from 1 of 13 Dectin 2 antibodies, which have been validated in experiments with 6 publications and 11 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for...
Antibodies that detect Dectin 2 can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA, Flow Cytometry and Immunocytochemistry. These antibodies target Dectin 2 in Human, Mouse, Rat and Non-human primate samples. Our Dectin 2 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Sheep, Goat and Mouse. Find the Dectin 2 antibody that fits your needs. Choose from 1 of 13 Dectin 2 antibodies, which have been validated in experiments with 6 publications and 11 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
Dectin-2 is a C-type lectin expressed by dendritic cells, macrophages and inflammatory monocytes. It is a type II membrane receptor, with a short cytoplasmic tail, and a C-terminal C-type lectin domain. Dectin-2 is a receptor with specificity for high mannose structures and mediates cytokine production from DC and other antigen presenting cells. Though, Dectin-2 has no obvious signaling motifs attached to CP tail, reports indicate that Dectin-2 employs FcRg for internalization and to activate NF-kappaB pathway for cytokine production. Though it shares only 20-25% of homology with Dectin-1, it functions similarly as pattern recognition receptor (PRR) for fungal infections, to activate both innate (Syk-CARD9 innate signaling pathway) and adaptive immune responses (by activation of DC) to fungal infections. Thus Dectin-2 is a connector molecule of both innate and adaptive immunity functioning at DC level.
同义词
Clec4n; CLEC6A; Clec6a-ps1; CLECSF10; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 10; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 10; C-type lectin domain family 4, member n; C-type lectin domain family 6 member A; C-type lectin domain family 6, member A; C-type lectin domain family 6, member A, pseudogene 1; C-type lectin superfamily member 10; DC-associated C-type lectin 2; dectin 2; DECTIN2; dectin-2; Dectin-2p; Dendritic cell-associated C-type lectin 2; natural killer complex lectin; Nkcl
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